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Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutations

BACKGROUND: Despite the remarkable advances in the early diagnosis and treatment, overall 5-year survival rate of patients with pancreatic cancer is less than 10%. Gemcitabine (GEM), a cytidine nucleoside analogue and ribonucleotide reductase inhibitor, is a primary option for patients with advanced...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Ozaki, Toshinori, Yu, Meng, Yin, Danjing, Sun, Dan, Zhu, Yuyan, Bu, Youquan, Sang, Meixiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861661/
https://ncbi.nlm.nih.gov/pubmed/29558908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4217-9
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