Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder

Defects in neurogenesis alter brain circuit formations and may lead to neurodevelopmental disorders such as autism and schizophrenia. Histone H2A.z, a variant of histone H2A, plays critical roles in chromatin structure and epigenetic regulation, but its function and mechanism in brain development re...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Shen, Tianjin, Ji, Fen, Wang, Yuanyuan, Lei, Xuepei, Zhang, Dongming, Jiao, Jianwei
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861433/
https://ncbi.nlm.nih.gov/pubmed/29294103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1295
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