Naltrexone Reverses Ethanol Preference and Protein Kinase C Activation in Drosophila melanogaster

Alcohol use disorder (AUD) is a major health, social and economic problem for which there are few effective treatments. The opiate antagonist naltrexone is currently prescribed clinically with mixed success. We have used naltrexone in an established behavioral assay (CAFE) in Drosophila melanogaster...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Koyyada, Rajeswari, Latchooman, Nilesh, Jonaitis, Julius, Ayoub, Samir S., Corcoran, Olivia, Casalotti, Stefano O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861182/
https://ncbi.nlm.nih.gov/pubmed/29593550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00175
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