Whole-Inactivated Influenza Virus Is a Potent Adjuvant for Influenza Peptides Containing CD8(+) T Cell Epitopes

Influenza peptide antigens coding for conserved T cell epitopes have the capacity to induce cross-protective influenza-specific immunity. Short peptide antigens used as a vaccine, however, often show poor immunogenicity. In this study, we demonstrate that whole-inactivated influenza virus (WIV) acts...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Soema, Peter C., Rosendahl Huber, Sietske K., Willems, Geert-Jan, Jacobi, Ronald, Hendriks, Marion, Soethout, Ernst, Jiskoot, Wim, de Jonge, Jørgen, van Beek, Josine, Kersten, Gideon F. A., Amorij, Jean-Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861146/
https://ncbi.nlm.nih.gov/pubmed/29593747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00525
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