Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion

Transient receptor potential vanilloid 4 (TRPV4) cation channels are functional in all renal vascular segments and mediate endothelium-dependent vasorelaxation. Moreover, they are expressed in distinct parts of the tubular system and activated by cell swelling. Ischaemia/reperfusion injury (IRI) is...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Mannaa, Marwan, Markó, Lajos, Balogh, András, Vigolo, Emilia, N’diaye, Gabriele, Kaßmann, Mario, Michalick, Laura, Weichelt, Ulrike, Schmidt–Ott, Kai M., Liedtke, Wolfgang B., Huang, Yu, Müller, Dominik N., Kuebler, Wolfgang M., Gollasch, Maik
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861116/
https://ncbi.nlm.nih.gov/pubmed/29559678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23165-0
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