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Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling

Undecaprenyl pyrophosphate phosphatase (UppP) is an integral membrane protein that recycles the lipid carrier essential to the ongoing biosynthesis of the bacterial cell wall. Individual building blocks of peptidoglycan are assembled in the cytoplasm on undecaprenyl phosphate (C55-P) before being fl...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Workman, Sean D., Worrall, Liam J., Strynadka, Natalie C. J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861054/
https://ncbi.nlm.nih.gov/pubmed/29559664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03547-8
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