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Proteomic Analysis of Sera from Individuals with Diffuse Cutaneous Systemic Sclerosis Reveals a Multianalyte Signature Associated with Clinical Improvement during Imatinib Mesylate Treatment

OBJECTIVE: Imatinib has been investigated for the treatment of systemic sclerosis (SSc) because of its ability to inhibit the platelet-derived growth factor receptor and transforming growth factor-β signaling pathways, which have been implicated in SSc pathogenesis. In a 12-month open-label clinical...

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Bibliografske podrobnosti
izdano v:J Rheumatol
Main Authors: Haddon, D. James, Wand, Hannah E., Jarrell, Justin A., Spiera, Robert F., Utz, Paul J., Gordon, Jessica K., Chung, Lorinda S.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860882/
https://ncbi.nlm.nih.gov/pubmed/28298564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3899/jrheum.160833
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