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The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function
The gene encoding for transcription factor 7-like 2 (TCF7L2) is the strongest type 2 diabetes mellitus (T2DM) candidate gene discovered to date. The TCF7L2 protein is a key transcriptional effector of the Wnt/β-catenin signaling pathway, which is an important developmental pathway that negatively re...
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Publicado no: | Diabetes |
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Principais autores: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Diabetes Association
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5860863/ https://ncbi.nlm.nih.gov/pubmed/29317436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0318 |
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