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The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function

The gene encoding for transcription factor 7-like 2 (TCF7L2) is the strongest type 2 diabetes mellitus (T2DM) candidate gene discovered to date. The TCF7L2 protein is a key transcriptional effector of the Wnt/β-catenin signaling pathway, which is an important developmental pathway that negatively re...

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Detalhes bibliográficos
Publicado no:Diabetes
Principais autores: Chen, Xi, Ayala, Iriscilla, Shannon, Chris, Fourcaudot, Marcel, Acharya, Nikhil K., Jenkinson, Christopher P., Heikkinen, Sami, Norton, Luke
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860863/
https://ncbi.nlm.nih.gov/pubmed/29317436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0318
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