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Method for the simulation of blood platelet shape and its evolution during activation

We present a simple physically based quantitative model of blood platelet shape and its evolution during agonist-induced activation. The model is based on the consideration of two major cytoskeletal elements: the marginal band of microtubules and the submembrane cortex. Mathematically, we consider t...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Moskalensky, Alexander E., Yurkin, Maxim A., Muliukov, Artem R., Litvinenko, Alena L., Nekrasov, Vyacheslav M., Chernyshev, Andrei V., Maltsev, Valeri P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860797/
https://ncbi.nlm.nih.gov/pubmed/29518073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005899
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