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Stoichiometric balance of protein copy numbers is measurable and functionally significant in a protein-protein interaction network for yeast endocytosis

Stoichiometric balance, or dosage balance, implies that proteins that are subunits of obligate complexes (e.g. the ribosome) should have copy numbers expressed to match their stoichiometry in that complex. Establishing balance (or imbalance) is an important tool for inferring subunit function and as...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Holland, David O., Johnson, Margaret E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860782/
https://ncbi.nlm.nih.gov/pubmed/29518071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006022
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