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New drug candidates for treatment of atypical meningiomas: An integrated approach using gene expression signatures for drug repurposing

BACKGROUND: Atypical meningiomas are common central nervous system neoplasms with high recurrence rate and poorer prognosis compared to their grade I counterparts. Surgical excision and radiotherapy remains the mainstay therapy but medical treatments are limited. We explore new drug candidates using...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zador, Zsolt, King, Andrew T., Geifman, Nophar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860760/
https://ncbi.nlm.nih.gov/pubmed/29558515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194701
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