Ursolic acid rich Ocimum sanctum L leaf extract loaded nanostructured lipid carriers ameliorate adjuvant induced arthritis in rats by inhibition of COX-1, COX-2, TNF-α and IL-1: Pharmacological and docking studies

BACKGROUND: Ursolic acid (UA) is a promising molecule with anti-inflammatory, analgesic and potential anti-arthritic activity. METHODS: This study was undertaken to make formulation and evaluation of Ocimum sanctum L. leaf extract (OLE) loaded nano-structured lipid carriers (OLE-NLCs) for improved t...

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Bibliographic Details
Published in:PLoS One
Main Authors: Ahmad, Aftab, Abuzinadah, Mohammed F., Alkreathy, Huda M., Banaganapalli, Babajan, Mujeeb, Mohd
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860693/
https://ncbi.nlm.nih.gov/pubmed/29558494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193451
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