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diffloop: a computational framework for identifying and analyzing differential DNA loops from sequencing data

SUMMARY: The 3D architecture of DNA within the nucleus is a key determinant of interactions between genes, regulatory elements, and transcriptional machinery. As a result, differences in DNA looping structure are associated with variation in gene expression and cell state. To systematically assess c...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Lareau, Caleb A, Aryee, Martin J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860605/
https://ncbi.nlm.nih.gov/pubmed/29028898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx623
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