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Stepwise inference of likely dynamic flux distributions from metabolic time series data

MOTIVATION: Most metabolic pathways contain more reactions than metabolites and therefore have a wide stoichiometric matrix that corresponds to infinitely many possible flux distributions that are perfectly compatible with the dynamics of the metabolites in a given dataset. This under-determinedness...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Faraji, Mojdeh, Voit, Eberhard O
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860468/
https://ncbi.nlm.nih.gov/pubmed/28334199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx126
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