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Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study

Specific alleles of the human leukocyte antigen (HLA)-DRB1 gene (HLA-DRB1) encode a “shared epitope” (SE) associated with rheumatoid arthritis (RA), especially more severe cyclic-citrullinated peptide antibody-positive (anti-CCP+) RA. We evaluated associations of number of SE alleles (0, 1, or 2) wi...

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Detalhes bibliográficos
Publicado no:Am J Epidemiol
Main Authors: Birru Talabi, Mehret, Mackey, Rachel H., Kuller, Lewis H., Dorman, Janice S., Deane, Kevin D., Robinson, William H., Walitt, Brian T., Chang, Yuefang, Holers, V. Michael, Liu, Simin, Moreland, Larry W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860272/
https://ncbi.nlm.nih.gov/pubmed/28459968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwx087
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