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A non-negative matrix factorization based method for predicting disease-associated miRNAs in miRNA-disease bilayer network

MOTIVATION: Identification of disease-associated miRNAs (disease miRNAs) is critical for understanding disease etiology and pathogenesis. Since miRNAs exert their functions by regulating the expression of their target mRNAs, several methods based on the target genes were proposed to predict disease...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Zhong, Yingli, Xuan, Ping, Wang, Xiao, Zhang, Tiangang, Li, Jianzhong, Liu, Yong, Zhang, Weixiong
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860200/
https://ncbi.nlm.nih.gov/pubmed/28968753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx546
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