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C. elegans ADARs antagonize silencing of cellular dsRNAs by the antiviral RNAi pathway

Cellular dsRNAs are edited by adenosine deaminases that act on RNA (ADARs). While editing can alter mRNA-coding potential, most editing occurs in noncoding sequences, the function of which is poorly understood. Using dsRNA immunoprecipitation (dsRIP) and RNA sequencing (RNA-seq), we identified 1523...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Reich, Daniel P., Tyc, Katarzyna M., Bass, Brenda L.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859968/
https://ncbi.nlm.nih.gov/pubmed/29483152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.310672.117
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