Effect of tocotrienol from Bixa orellana (annatto) on bone microstructure, calcium content, and biomechanical strength in a model of male osteoporosis induced by buserelin

BACKGROUND: Patients receiving androgen deprivation therapy experience secondary hypogonadism, associated bone loss, and increased fracture risk. It has been shown that tocotrienol from Bixa orellana (annatto) prevents skeletal microstructural changes in rats experiencing primary hypogonadism. Howev...

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Udgivet i:Drug Des Devel Ther
Main Authors: Mohamad, Nur-Vaizura, Ima-Nirwana, Soelaiman, Chin, Kok-Yong
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859897/
https://ncbi.nlm.nih.gov/pubmed/29588572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S158410
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