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Effect of tocotrienol from Bixa orellana (annatto) on bone microstructure, calcium content, and biomechanical strength in a model of male osteoporosis induced by buserelin

BACKGROUND: Patients receiving androgen deprivation therapy experience secondary hypogonadism, associated bone loss, and increased fracture risk. It has been shown that tocotrienol from Bixa orellana (annatto) prevents skeletal microstructural changes in rats experiencing primary hypogonadism. Howev...

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Publicado en:Drug Des Devel Ther
Autores principales: Mohamad, Nur-Vaizura, Ima-Nirwana, Soelaiman, Chin, Kok-Yong
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859897/
https://ncbi.nlm.nih.gov/pubmed/29588572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S158410
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