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A functional SNP upstream of the ADRB2 gene is associated with COPD

BACKGROUND: Previous studies have suggested that β(2)-adrenergic receptor (ADRB2) is associated with COPD. However, the role of genetic polymorphisms in ADRB2 on COPD has not been evaluated yet. METHODS: In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-tim...

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Dettagli Bibliografici
Pubblicato in:Int J Chron Obstruct Pulmon Dis
Autori principali: Li, Jin-Xiu, Fu, Wei-Ping, Zhang, Jing, Zhang, Xiao-Hua, Sun, Chang, Dai, Lu-Ming, Zhong, Li, Yu, Li, Zhang, Ya-Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859892/
https://ncbi.nlm.nih.gov/pubmed/29588580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S151153
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