Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming

BACKGROUND: While a shift towards non-viral and animal component-free methods of generating induced pluripotent stem (iPS) cells is preferred for safer clinical applications, there is still a shortage of reliable cell sources and protocols for efficient reprogramming. METHODS: Here, we show a robust...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Thekkeparambil Chandrabose, Srijaya, Sriram, Sandhya, Subramanian, Subha, Cheng, Shanshan, Ong, Wee Kiat, Rozen, Steve, Kasim, Noor Hayaty Abu, Sugii, Shigeki
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859503/
https://ncbi.nlm.nih.gov/pubmed/29559008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0796-2
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