Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury

BACKGROUND: In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after nerve injury is sexually dimorphic remains unknow...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Remacle, Albert G., Hullugundi, Swathi K., Dolkas, Jennifer, Angert, Mila, Chernov, Andrei V., Strongin, Alex Y., Shubayev, Veronica I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859418/
https://ncbi.nlm.nih.gov/pubmed/29558999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1123-7
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