Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function

BACKGROUND: Inhibition of the nuclear factor kappa beta (NF-κβ) pathway has been proposed as a therapeutic target due to its key role in the expression of pro-inflammatory genes, including pro-inflammatory cytokines, chemokines, and adhesion molecules. Caffeic acid phenethyl ester (CAPE) is a natura...

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Publicado en:Inflammopharmacology
Autores principales: Khan, Mohammed N., Lane, Majella E., McCarron, Paul A., Tambuwala, Murtaza M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859149/
https://ncbi.nlm.nih.gov/pubmed/28528363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10787-017-0364-x
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