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New insights into the earliest stages of colorectal tumorigenesis

INTRODUCTION: Tumors in the large intestine have been postulated to arise via a stepwise accumulation of mutations, a process that takes up to 20 years. Recent advances in lineage tracing and DNA sequencing, however, are revealing new evolutionary models that better explain the vast amount of hetero...

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Detalhes bibliográficos
Publicado no:Expert Rev Gastroenterol Hepatol
Main Authors: Sievers, Chelsie K., Grady, William M., Halberg, Richard B., Pickhardt, Perry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859121/
https://ncbi.nlm.nih.gov/pubmed/28503955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17474124.2017.1330150
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