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New insights into the earliest stages of colorectal tumorigenesis

INTRODUCTION: Tumors in the large intestine have been postulated to arise via a stepwise accumulation of mutations, a process that takes up to 20 years. Recent advances in lineage tracing and DNA sequencing, however, are revealing new evolutionary models that better explain the vast amount of hetero...

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Bibliografski detalji
Izdano u:Expert Rev Gastroenterol Hepatol
Glavni autori: Sievers, Chelsie K., Grady, William M., Halberg, Richard B., Pickhardt, Perry J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859121/
https://ncbi.nlm.nih.gov/pubmed/28503955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17474124.2017.1330150
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