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The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development

Streptomycetes are notable for their complex life cycle and production of most clinically important antibiotics. A key factor that controls entry into development and the onset of antibiotic production is the 68-residue protein, BldC. BldC is a putative DNA-binding protein related to MerR regulators...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Schumacher, Maria A., den Hengst, Chris D., Bush, Matthew J., Le, T. B. K., Tran, Ngat T., Chandra, Govind, Zeng, Wenjie, Travis, Brady, Brennan, Richard G., Buttner, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859096/
https://ncbi.nlm.nih.gov/pubmed/29556010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03576-3
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