Antibody-dependent enhancement of severe dengue disease in humans

For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to enhance viral replication in vitro and severe disease in animal models. Although suspected, such antibody-dependent enhancement of severe disease has not been shown to occur in humans. Using multiple statistica...

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Dettagli Bibliografici
Pubblicato in:Science
Autori principali: Katzelnick, Leah C., Gresh, Lionel, Halloran, M. Elizabeth, Mercado, Juan Carlos, Kuan, Guillermina, Gordon, Aubree, Balmaseda, Angel, Harris, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2017
Soggetti:
Virology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858873/
https://ncbi.nlm.nih.gov/pubmed/29097492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan6836
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