p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice

The TORC1 pathway is necessary for ribosomal biogenesis and initiation of protein translation. Furthermore, the differentiation of Th1 and Th17 cells requires TORC1 activity. To investigate the role of the TORC1 pathway in the differentiation of Th1 and/or Th17 cells in more detail, we compared the...

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Foilsithe in:Eur J Immunol
Main Authors: Sasaki, Carl Y., Chen, Gang, Munk, Rachel, Eitan, Erez, Martindale, Jennifer, Longo, Dan L., Ghosh, Paritosh
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858723/
https://ncbi.nlm.nih.gov/pubmed/26514620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445422
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