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Copper-catalyzed aminoalkynylation of alkenes with hypervalent iodine reagents

A copper-catalyzed aminoalkynylation of alkenes is achieved with ethynylbenziodoxolone (EBX) reagents under mild conditions with only 1 mol% copper catalyst. This transformation allows for rapid construction of diverse important azahetereocycles and installation of valuable alkyne groups in one step...

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Publicado en:Chem Sci
Main Authors: Shen, Kun, Wang, Qiu
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857935/
https://ncbi.nlm.nih.gov/pubmed/29568474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03420b
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