Randomised controlled trial protocol to evaluate a fixed dose prothrombin complex concentrate against the variable dose in vitamin K antagonist related bleeding (PROPER3)

INTRODUCTION: There is currently little evidence for the optimal dosing strategy of four-factor prothrombin complex concentrates (PCC) in vitamin K antagonist (VKA)-related bleeds. The generally accepted dosing strategy is the use of a variable dose calculated using patient-specific characteristics...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Abdoellakhan, Rahat A, Khorsand, Nakisa, Van Hest, Reinier M, Veeger, Nic, Ter Avest, Ewoud, Ypma, Paula F, Faber, Laura M, Meijer, Karina
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Haematology (Incl Blood Transfusion)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857685/
https://ncbi.nlm.nih.gov/pubmed/29540424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-020764
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