Kindlin-1 promotes pulmonary breast cancer metastasis

In breast cancer, increased expression of the cytoskeletal adaptor protein Kindlin-1 has been linked to increased risks of lung metastasis, but the functional basis is unknown. Here we show that in a mouse model of polyomavirus middle T antigen-induced mammary tumorigenesis, loss of Kindlin-1 reduce...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Sarvi, Sana, Patel, Hitesh, Li, Jun, Dodd, Georgia L., Creedon, Helen, Muir, Morwenna, Ward, Jocelyn, Dawson, John C., Lee, Martin, Culley, Jayne, Salter, Donald M., Sims, Andrew H., Byron, Adam, Brunton, Valerie G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857359/
https://ncbi.nlm.nih.gov/pubmed/29330144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1518
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