Recognition of DHN-melanin by MelLec, is required for protective immunity to Aspergillus

Our resistance to infection is critically dependent upon the ability of pattern recognition receptors to recognise microbial invasion and induce protective immune responses. One such family of receptors are the C-type lectins, which play central roles in antifungal immunity1. These receptors activat...

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Veröffentlicht in:Nature
Hauptverfasser: Stappers, Mark H.T., Clark, Alexandra E., Aimanianda, Vishukumar, Bidula, Stefan, Reid, Delyth M., Asamaphan, Patawee, Hardison, Sarah E., Dambuza, Ivy M., Valsecchi, Isabel, Kerscher, Bernhard, Plato, Anthony, Wallace, Carol A., Yuecel, Raif, Hebecker, Betty, da Glória Teixeira Sousa, Maria, Cunha, Cristina, Liu, Yan, Feizi, Ten, Brakhage, Axel A., Kwon-Chung, Kyung J., Gow, Neil A. R., Zanda, Matteo, Piras, Monica, Zanato, Chiara, Jaeger, Martin, Netea, Mihai G., van de Veerdonk, Frank L., Lacerda, João F., Campos, António, Carvalho, Agostinho, Willment, Janet A., Latgé, Jean-Paul, Brown, Gordon D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857201/
https://ncbi.nlm.nih.gov/pubmed/29489751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25974
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