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Investigation of nepetolide as a novel lead compound: Antioxidant, antimicrobial, cytotoxic, anticancer, anti-inflammatory, analgesic activities and molecular docking evaluation

In the present study, we describe various pharmacological effects and computational analysis of nepetolide, a tricyclic clerodane-type diterpene, isolated from Nepeta suavis. Nepetolide concentration-dependently (1.0–1000 µg/mL) exhibited 1,1-diphenyl,2-picrylhydrazyl free radical scavenging activit...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: ur Rehman, Tanzeel, Khan, Arif-ullah, Abbas, Azar, Hussain, Javid, Khan, Farman Ullah, Stieglitz, Kimberly, Ali, Shamsher
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856943/
https://ncbi.nlm.nih.gov/pubmed/29556134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2017.12.019
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