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An acquired and a native penicillin-binding protein cooperate in building the cell wall of drug-resistant staphylococci

The blanket resistance of methicillin-resistant Staphylococcus aureus to all β-lactam antibiotics—which had such a devastating impact on chemotherapy of staphylococcal infections—is related to the properties of the key component of this resistance mechanism: the “acquired” penicillin-binding protein...

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Autori principali: Pinho, Mariana G., de Lencastre, Hermínia, Tomasz, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC58569/
https://ncbi.nlm.nih.gov/pubmed/11517340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191260798
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