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Clinical Pharmacokinetics and Pharmacodynamics of the Epidermal Growth Factor Receptor Inhibitor Panitumumab in the Treatment of Colorectal Cancer

Despite progress in the treatment of metastatic colorectal cancer (mCRC) in the last 15 years, it is still a condition with a relatively low 5-year survival rate. Panitumumab, a fully human monoclonal antibody directed against the epidermal growth factor receptor (EGFR), is able to prolong survival...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Principais autores: Ketzer, Sander, Schimmel, Kirsten, Koopman, Miriam, Guchelaar, Henk-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856878/
https://ncbi.nlm.nih.gov/pubmed/28853050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0590-9
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