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Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for nociception

All animals must detect noxious stimuli to initiate protective behavior, but the evolutionary origin of nociceptive systems is not well understood. Here, we show that noxious heat and irritant chemicals elicit robust escape behaviors in the planarian Schmidtea mediterranea, and that the conserved io...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Arenas, Oscar M., Zaharieva, Emanuela E., Para, Alessia, Vásquez-Doorman, Constanza, Petersen, Christian P., Gallio, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856474/
https://ncbi.nlm.nih.gov/pubmed/29184198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-017-0005-0
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