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Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages

Allergic bronchopulmonary aspergillosis (ABPA) in asthma is a severe, life-affecting disease that potentially affects over 4.8 million people globally. In the UK, ABPA is predominantly caused by the fungus Aspergillus fumigatus. Phagocytosis is important in clearance of this fungus, and Early Endoso...

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Foilsithe in:PLoS One
Main Authors: Overton, Nicola L. D., Brakhage, Axel A., Thywißen, Andreas, Denning, David W., Bowyer, Paul
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856258/
https://ncbi.nlm.nih.gov/pubmed/29547649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185706
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