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Alterations of Subchondral Bone Progenitor Cells in Human Knee and Hip Osteoarthritis Lead to a Bone Sclerosis Phenotype

Subchondral bone tissue plays a key role in the initiation and progression of human and experimental osteoarthritis and has received considerable interest as a treatment target. Elevated bone turnover and remodeling leads to subchondral bone sclerosis that is characterized by an increase in bone mat...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bianco, Daniel, Todorov, Atanas, Čengić, Tomislav, Pagenstert, Geert, Schären, Stefan, Netzer, Cordula, Hügle, Thomas, Geurts, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855697/
https://ncbi.nlm.nih.gov/pubmed/29415458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020475
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