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Nanobody Based Dual Specific CARs

Recent clinical trials have shown that adoptive chimeric antigen receptor (CAR) T cell therapy is a very potent and possibly curative option in the treatment of B cell leukemias and lymphomas. However, targeting a single antigen may not be sufficient, and relapse due to the emergence of antigen nega...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: De Munter, Stijn, Ingels, Joline, Goetgeluk, Glenn, Bonte, Sarah, Pille, Melissa, Weening, Karin, Kerre, Tessa, Abken, Hinrich, Vandekerckhove, Bart
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855625/
https://ncbi.nlm.nih.gov/pubmed/29385713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020403
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