Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function

The axons of retinal ganglion cells (RGCs) are topographically sorted before they arrive at the optic tectum. This pre-target sorting, typical of axon tracts throughout the brain, is poorly understood. Here, we show that cytoplasmic FMR1-interacting proteins (CYFIPs) fulfill non-redundant functions...

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Publicat a:Neuron
Autors principals: Cioni, Jean-Michel, Wong, Hovy Ho-Wai, Bressan, Dario, Kodama, Lay, Harris, William A., Holt, Christine E.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855093/
https://ncbi.nlm.nih.gov/pubmed/29518358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.027
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