Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion by Plasmodium falciparum

Effective vaccines against malaria caused by Plasmodium falciparum are still lacking, and the molecular mechanism of the host-parasite interaction is not fully understood. Here we demonstrate that the interaction of RAP2, a parasite-secreted rhoptry protein that functions in the parasitophorous vacu...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Zhang, Meng-Yao, Zhang, Yang, Wu, Xiao-Dong, Zhang, Kun, Lin, Peng, Bian, Hui-Jie, Qin, Min-Min, Huang, Wan, Wei, Ding, Zhang, Zhao, Wu, Jiao, Chen, Ruo, Feng, Fei, Wang, Bin, Nan, Gang, Zhu, Ping, Chen, Zhi-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854849/
https://ncbi.nlm.nih.gov/pubmed/29352039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-802918
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