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Neuropeptide S Induces Acute Anxiolysis by Phospholipase C-Dependent Signaling within the Medial Amygdala

Neuropeptide S (NPS) is an important anxiolytic substance of the brain. However, the signaling pathways downstream of NPS receptor (NPSR) activation, underlying the behavioral effect of NPS, remain largely unknown. Here, we show that bilateral microinfusion of NPS (0.2 nmol/0.5 μl) into the medial a...

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Publicado en:Neuropsychopharmacology
Autores principales: Grund, Thomas, Neumann, Inga D
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854792/
https://ncbi.nlm.nih.gov/pubmed/28805209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.169
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