Synthesis, molecular docking, ctDNA interaction, DFT calculation and evaluation of antiproliferative and anti-Toxoplasma gondii activities of 2,4-diaminotriazine-thiazole derivatives

Synthesis, characterization, and investigation of antiproliferative activities against human cancer cell lines (MV4-11, MCF-7, and A549) and Toxoplasma gondii parasite of twelve novel 2,4-diaminotriazine-thiazoles are presented. The toxicity of the compounds was studied at three different cell types...

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Detalhes bibliográficos
Publicado no:Med Chem Res
Main Authors: Łączkowski, Krzysztof Z., Anusiak, Joanna, Świtalska, Marta, Dzitko, Katarzyna, Cytarska, Joanna, Baranowska-Łączkowska, Angelika, Plech, Tomasz, Paneth, Agata, Wietrzyk, Joanna, Białczyk, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854716/
https://ncbi.nlm.nih.gov/pubmed/29576720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-018-2136-6
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