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Mitochondrial Sirtuin 4 Resolves Immune Tolerance in Monocytes by Rebalancing Glycolysis and Glucose Oxidation Homeostasis

The goal of this investigation was to define the molecular mechanism underlying physiologic conversion of immune tolerance to resolution of the acute inflammatory response, which is unknown. An example of this knowledge gap and its clinical importance is the broad-based energy deficit and immunometa...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Immunol
Main Authors: Tao, Jie, Zhang, Jingpu, Ling, Yun, McCall, Charles E., Liu, Tie Fu
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854658/
https://ncbi.nlm.nih.gov/pubmed/29593712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00419
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