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Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death

Excitotoxicity leads to the activation of a cytotoxic cascade that causes neuronal death. In the retina, retinal ganglion cells (RGCs) die after an excitotoxic insult. Multiple pathways have been proposed to contribute to RGC death after an excitotoxic insult, including TNF signaling, JNK activation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fahrenthold, Berkeley K., Fernandes, Kimberly A., Libby, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854579/
https://ncbi.nlm.nih.gov/pubmed/29545615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22848-y
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