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Copy Number Changes Identified Using Whole Exome Sequencing in Non-Syndromic Cleft Lip and Palate in a Honduran Population

BACKGROUND: The majority of cleft lip with or without cleft palate (CL/P) cases appear as an isolated, non-syndromic entity (NSCLP). With the advent of next generation sequencing, whole exome sequencing (WES) has been used to identify single nucleotide variants and insertion/deletions which cause or...

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Detalhes bibliográficos
Publicado no:Birth Defects Res
Main Authors: Cai, Yi, Patterson, Karynne E, Reinier, Frederic, Keesecker, Sarah E, Blue, Elizabeth, Bamshad, Michael, Haddad, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854563/
https://ncbi.nlm.nih.gov/pubmed/28748635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdr2.1063
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