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Physiological oxygen culture reveals retention of metabolic memory in human induced pluripotent stem cells

Reprogramming somatic cells to a pluripotent cell state (induced Pluripotent Stem (iPS) cells) requires reprogramming of metabolism to support cell proliferation and pluripotency, most notably changes in carbohydrate turnover that reflect a shift from oxidative to glycolytic metabolism. Some aspects...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Harvey, Alexandra J., O’Brien, Carmel, Lambshead, Jack, Sheedy, John R., Rathjen, Joy, Laslett, Andrew L., Gardner, David K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854358/
https://ncbi.nlm.nih.gov/pubmed/29543848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193949
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