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Paper-based detection of HIV-1 drug resistance using isothermal amplification and an oligonucleotide ligation assay

Regular HIV-1 viral load monitoring is the standard of care to assess antiretroviral therapy effectiveness in resource-rich settings. Persistently elevated viral loads indicate virologic failure (VF), which warrants HIV drug resistance testing (HIVDRT) to allow individualized regimen switches. Howev...

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Bibliografiske detaljer
Udgivet i:Anal Biochem
Main Authors: Natoli, Mary E., Rohrman, Brittany A., De Santiago, Carolina, van Zyl, Gert U., Richards-Kortum, Rebecca R.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854266/
https://ncbi.nlm.nih.gov/pubmed/29229373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2017.12.008
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