CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term Survival

Cytomegalovirus (CMV) infection sometimes causes large expansions of CMV-specific T cells, particularly in older people. This is believed to undermine immunity to other pathogens and to accelerate immunosenescence. While multiple different CMV proteins are recognized, most publications on age-relate...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: Bajwa, Martha, Vita, Serena, Vescovini, Rosanna, Larsen, Martin, Sansoni, Paolo, Terrazzini, Nadia, Caserta, Stefano, Thomas, David, Davies, Kevin A., Smith, Helen, Kern, Florian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Major Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854018/
https://ncbi.nlm.nih.gov/pubmed/28199648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix080
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