Diverse Streptococcus pneumoniae Strains Drive a Mucosal-Associated Invariant T-Cell Response Through Major Histocompatibility Complex class I–Related Molecule–Dependent and Cytokine-Driven Pathways

Mucosal-associated invariant T (MAIT) cells represent an innate T-cell population that can recognize ligands generated by the microbial riboflavin synthesis pathway, presented via the major histocompatibility complex class I–related molecule (MR1). Streptococcus pneumoniae is a major human pathogen...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Kurioka, Ayako, van Wilgenburg, Bonnie, Javan, Reza Rezaei, Hoyle, Ryan, van Tonder, Andries J, Harrold, Caroline L, Leng, Tianqi, Howson, Lauren J, Shepherd, Dawn, Cerundolo, Vincenzo, Brueggemann, Angela B, Klenerman, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854017/
https://ncbi.nlm.nih.gov/pubmed/29267892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix647
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