Suppressor Cell–Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis

Host-directed therapies that augment host immune effector mechanisms may serve as important adjunctive therapies for tuberculosis treatment. We evaluated the activity of denileukin diftitox in an acute mouse model of tuberculosis (TB) infection and analyzed the cellular composition and bacterial bur...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Gupta, Shashank, Cheung, Laurene, Pokkali, Supriya, Winglee, Kathryn, Guo, Haidan, Murphy, John R., Bishai, William R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853937/
https://ncbi.nlm.nih.gov/pubmed/28863467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix208
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