Serial Vaccination and the Antigenic Distance Hypothesis: Effects on Influenza Vaccine Effectiveness During A(H3N2) Epidemics in Canada, 2010–2011 to 2014–2015

BACKGROUND. The antigenic distance hypothesis (ADH) predicts that negative interference from prior season’s influenza vaccine (v1) on the current season’s vaccine (v2) protection may occur when the antigenic distance is small between v1 and v2 (v1 ≈ v2) but large between v1 and the current epidemic...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Skowronski, Danuta M., Chambers, Catharine, De Serres, Gaston, Sabaiduc, Suzana, Winter, Anne-Luise, Dickinson, James A., Gubbay, Jonathan B., Fonseca, Kevin, Drews, Steven J., Charest, Hugues, Martineau, Christine, Krajden, Mel, Petric, Martin, Bastien, Nathalie, Li, Yan, Smith, Derek J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853783/
https://ncbi.nlm.nih.gov/pubmed/28180277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix074
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